The “Dysplastic Nevus” Conundrum: A Look Back, a Peek Forward

Dysplastic nevus (atypical nevus).

Atypical nevum (dysplastic) is considered an important factor associated with increased risk of developing cutaneous melanoma. It is believed that atypical nevi are precursor lesions of cutaneous melanoma. They may be present in patients with multiple melanocytic nevi (atypical nevus syndrome) or isolated and in small numbers in a non-familial context. The disease usually begins at puberty and ...

ILP: A Short Look Back and a Longer Look Forward

Inductive logic programming (ILP) is built on a foundation laid by research in machine learning and computational logic. Armed with this strong foundation, ILP has been applied to important and interesting problems in the life sciences, engineering and the arts. This paper begins by briefly reviewing some example applications, in order to illustrate the benefits of ILP. In turn, the application...

Dysplastic Nevus: A Fake Lesion?

The story of “dysplastic nevus” dates as far back as 1978 when W.H. Clark and colleagues [1] reported a group of melanocytic lesions with atypical clinical and histological features. Such melanocytic nevi were regarded as precursors of melanoma in patients with multiple nevi and/or family history of melanoma and the term of “dysplastic nevus” soon after entered the diagnostic jargon. The concep...

Atypical Mole (Dysplastic Nevus)

Dysplastic pointillist nevus.

BACKGROUND Three cases of pointillist nevus, which is a distinctive clinical type of benign melanocytic nevus with variegated pigment, have been described in the literature to date. OBSERVATIONS A 24-year-old man presented with an acquired melanocytic lesion composed of multiple tiny pigmented dots. Dermoscopy revealed multiple brown globules on a reddish skin-colored background, and histolog...